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Rapid and synchronous chemical induction of replicative‐like senescence via a small molecule inhibitor |
| Palikyras S, Sofiadis K, (...), Papantonis A | Aging Cell | 2024 | | |
In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization |
| Oberbeckmann E, Quililan K, Cramer P, Oudelaar AM | Nature Genetics | 2024 | | |
Hypoxia-driven deSUMOylation of EXOSC10 promotes adaptive changes in the transcriptome profile |
| Filippopoulou C, Thomé CC, (...), Chachami G | Cellular and Molecular Life Sciences | 2024 | | |
Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair |
| Kokic G, Yakoub G, (...), Luijsterburg MS | Nature Structural & Molecular Biology | 2024 | | |
Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1 |
| Düring J, Wolter M, (...), Lorenz S | Nature Structural & Molecular Biology | 2024 | | |
RfaA (YqhY), a novel adaptor protein, controls metabolite-sensitive protein degradation in Bacillus subtilis |
| Wicke D, Lentes S, (...), Stülke J | bioRxiv | 2024 | | |
Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins |
| Zhang Z, Kumar V, (...), Lührmann R | EMBO Journal | 2024 | | |
Structure of the multi-subunit chloroplast RNA polymerase |
| do Prado PF, Ahrens FM, (...), Hillen HS | Molecular Cell | 2024 | | |
Atomic Mutagenesis of N6-Methyladenosine Reveals Distinct Recognition Modes by Human m6A Reader and Eraser Proteins | | Seitz F, Jungnickel T, (...), Höbartner C | Journal of the American Chemical Society | 2024 | | |
Genome organization across scales: mechanistic insights from <i>in vitro</i> reconstitution studies | | Oberbeckmann E, Oudelaar AM | Biochemical Society Transactions | 2024 | | |
RfaA (YqhY), a novel adaptor protein, controls metabolite-sensitive protein degradation in Bacillus subtilis |
| Stülke J, Wicke D, (...), Feussner I | Researchsquare | 2024 | | |
Structural basis of Integrator-dependent RNA polymerase II termination |
| Fianu I, Ochmann M, (...), Cramer P | Nature | 2024 | | |
Molecular basis of human nuclear and mitochondrial tRNA 3'-processing |
| Bhatta A, Kuhle B, (...), Hillen H | bioRxiv | 2024 | | |
How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA | | Höbartner C, Bohnsack KE, Bohnsack MT | Annual Review of Biochemistry | 2024 | | |
Coenzyme A biosynthesis in Bacillus subtilis: Discovery of a novel precursor metabolite for salvage and its uptake system |
| Warneke R, Herzberg C, (...), Stülke J | bioRxiv | 2024 | | |
Intensity and retention time prediction improves the rescoring of protein‐nucleic acid cross‐links |
| Siraj A, Bouwmeester R, (...), Sachsenberg T | Proteomics | 2024 | | |
Pervasive structural heterogeneity rewires glioblastoma chromosomes to sustain patient-specific transcriptional programs |
| Xie T, Danieli-Mackay A, (...), Papantonis A | Nature Communications | 2024 | | |
Translation factor accelerating peptide bond formation on the ribosome: EF-P and eIF5A as entropic catalysts and a potential drug targets |
| Mudryi V, Peske F, Rodnina M | BBA Advances | 2023 | | |
Understudied Proteins and Understudied Functions in the Model Bacterium Bacillus subtilis - a Major Challenge in Current Research |
| Stülke J, Wicke D, Meißner J, Warneke R, Elfmann C | Authorea | 2023 | | |
Understudied Proteins and Understudied Functions in the Model Bacterium Bacillus subtilis – a Major Challenge in Current Research |
| Wicke D, Meißner J, Warneke R, Elfmann C, Stülke J | Molecular Microbiology | 2023 | | |
PAE Viewer: A webserver for the interactive visualization of the predicted aligned error for multimer structure predictions and crosslinks |
| Elfmann C, Stülke J | bioRxiv | 2023 | | |
PAE viewer: a webserver for the interactive visualization of the predicted aligned error for multimer structure predictions and crosslinks |
| Elfmann C, Stülke J | Nucleic Acids Research | 2023 | | |
Bacillus subtilis, a Swiss Army Knife in Science and Biotechnology | | Stülke J, Grüppen A, Bramkamp M, Pelzer S | Journal of Bacteriology | 2023 | | |
N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing |
| Wang C, Ulryck N, (...), Graille M | Nucleic Acids Research | 2023 | | |
Ribozyme‐Catalyzed Late‐Stage Functionalization and Fluorogenic Labeling of RNA | | Scheitl CPM, Okuda T, Adelmann J, Höbartner C | Angewandte Chemie | 2023 | | |
Extreme structural heterogeneity rewires glioblastoma chromosomes to sustain patient-specific transcriptional programs |
| Xie T, Danieli-Mackay A, (...), Papantonis A | bioRxiv | 2023 | | |
Hypoxia-driven deSUMOylation of EXOSC10 promotes adaptive changes in the transcriptome profile |
| Filippopoulou C, Thome CC, (...), Chachami G | bioRxiv | 2023 | | |
Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex |
| Jia J, Hilal T, (...), Wahl MC | Nature Communications | 2023 | | |
Human TRMT2A methylates tRNA and contributes to translation fidelity |
| Witzenberger M, Burczyk S, (...), Niessing D | Nucleic Acids Research | 2023 | | |
The Mediator complex regulates enhancer-promoter interactions |
| Ramasamy S, Aljahani A, (...), Oudelaar AM | Nature Structural & Molecular Biology | 2023 | | |
A viral ADP-ribosyltransferase attaches RNA chains to host proteins |
| Wolfram-Schauerte M, Pozhydaieva N, (...), Höfer K | Nature | 2023 | | |
Cellular functions of eukaryotic RNA helicases and their links to human diseases | | Bohnsack KE, Yi S, Venus S, Jankowsky E, Bohnsack MT | Nature Reviews Molecular Cell Biology | 2023 | | |
Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm |
| Grahn E, Kaufmann SV, (...), Kaupp U | Nature Communications | 2023 | | |
Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices |
| Jentoft IM, Bäuerlein FJ, (...), Schuh M | Cell | 2023 | | |
Structure of the transcribing RNA polymerase II–Elongin complex |
| Chen Y, Kokic G, Dienemann C, Dybkov O, Urlaub H, Cramer P | Nature Structural & Molecular Biology | 2023 | | |
Approaching automation of multiple instance orchestration of the menoci web portal |
| Freckmann L, Henke C, (...), Kusch H | Bausteine Forschungsdatenmanagement | 2023 | | |
Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications | | Helm M, Bohnsack MT, (...), Stafforst T | ACS Chemical Biology | 2023 | | |
The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in <i>Bacillus subtilis in vitro</i> |
| Wicke D, Neumann P, (...), Stülke J | Nucleic Acids Research | 2023 | | |
Age-associated transcriptional stress due to accelerated elongation and increased stalling of RNAPII |
| Papadakis A, Gyenis A, Pothof J, H. J. Hoeijmakers J, Papantonis A, Beyer A | Nature Genetics | 2023 | | |
Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis |
| Dönig J, Mende H, (...), Müller S | Nature Communications | 2023 | | |
GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners |
| Kanwal N, Krogh N, (...), Bohnsack M | Nucleic Acids Research | 2023 | | |
The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress |
| Jansen J, Bohnsack KE, Böhlken-Fascher S, Bohnsack MT, Dobbelstein M | bioRxiv | 2023 | | |
The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in<i>Bacillus subtilis</i> |
| Wicke D, Neumann P, (...), Stülke J | bioRxiv | 2023 | | |