| Property |
Value |
| Working Groups |
RG Rodnina |
| Subproject |
P15 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
41430436 |
| DOI |
10.1038/s41586-025-10058-2 |
| Publication Year |
2025 |
| Title |
NAC controls nascent chain fate through tunnel sensing and chaperone action |
| Journal |
Nature |
| ISSN |
0028-0836 |
| eISSN |
1476-4687 |
| URL |
https://doi.org/10.1038/s41586-025-10058-2 |
| Journal Abbreviation |
Nature |
| Authors |
Lee JH, Rabl L, Gamerdinger M, Goyal V, Khakzar KM, Barbosa NM, Abramovich J, Morales-Polanco F, Köhler A, Samatova E, Rodnina MV, Deuerling E, Frydman J |
| First Author |
Lee JH |
| Last Author |
Frydman J |
External Resources
1654https://www.addgene.org/1654 Addgene identifier (1654, reused)
nature.c...-2.pdfhttps://www.nature.com/articles/s41586-025-10058-2.pdf Article fulltext
gro-2/153521http://resolver.sub.uni-goettingen.de/purl?gro-2/153521 GRO.publications identifier
GSE263659https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE263659 NCBI GEO Dataset (GSE263659)
GSE263661https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE263661 NCBI GEO Dataset (GSE263661)
6239https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=6239 NCBI taxonomy (Caenorhabditis elegans)
0000-0002-8663-3209https://orcid.org/0000-0002-8663-3209 ORCID identifier (Jae Ho Lee)
0000-0002-3736-9800https://orcid.org/0000-0002-3736-9800 ORCID identifier (Laurenz Rabl)
0000-0003-1483-8181https://orcid.org/0000-0003-1483-8181 ORCID identifier (Martin Gamerdinger)
0009-0006-1252-230Xhttps://orcid.org/0009-0006-1252-230X ORCID identifier (Vaishali Goyal)
0000-0002-3952-558Xhttps://orcid.org/0000-0002-3952-558X ORCID identifier (Natalia Moreira Barbosa)
0000-0001-9466-979Xhttps://orcid.org/0000-0001-9466-979X ORCID identifier (Juliana Abramovich)
0000-0002-7695-3081https://orcid.org/0000-0002-7695-3081 ORCID identifier (Fabián Morales-Polanco)
0009-0007-6155-4719https://orcid.org/0009-0007-6155-4719 ORCID identifier (Ann-Kathrin Köhler)
0000-0001-7508-8076https://orcid.org/0000-0001-7508-8076 ORCID identifier (Ekaterina Samatova)
0000-0003-0105-3879https://orcid.org/0000-0003-0105-3879 ORCID identifier (Marina V. Rodnina)
0000-0002-8905-0260https://orcid.org/0000-0002-8905-0260 ORCID identifier (Elke Deuerling)
0000-0003-2302-6943https://orcid.org/0000-0003-2302-6943 ORCID identifier (Judith Frydman)
102https://rdp.sfb1565.uni-goettingen.de/literature/publications/102 Published Data Registry entry (CRC 1565, preprint)
5/35https://rdp.sfb1565.uni-goettingen.de/archive/5/35 Research Data Archive (supplemental material)
03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
00f54p054https://ror.org/00f54p054 ROR identifier (00f54p054, Stanford University)
05qghxh33https://ror.org/05qghxh33 ROR identifier (05qghxh33, Stony Brook University)
0546hnb39https://ror.org/0546hnb39 ROR identifier (0546hnb39, University of Konstanz)
SCR_019715https://scicrunch.org/resolver/SCR_019715 SciCrunch identifier (RRID:SCR_019715, BioAnalyzer 2100)
SCR_005476https://scicrunch.org/resolver/SCR_005476 SciCrunch identifier (RRID:SCR_005476, Bowtie)
SCR_001802https://scicrunch.org/resolver/SCR_001802 SciCrunch identifier (RRID:SCR_001802, CASAVA)
SCR_011841https://scicrunch.org/resolver/SCR_011841 SciCrunch identifier (RRID:SCR_011841, cutadapt)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_007672https://scicrunch.org/resolver/SCR_007672 SciCrunch identifier (RRID:SCR_007672, Gene3D)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_023614https://scicrunch.org/resolver/SCR_023614 SciCrunch identifier (RRID:SCR_023614, Illumina NextSeq 2000 system)
SCR_016381https://scicrunch.org/resolver/SCR_016381 SciCrunch identifier (RRID:SCR_016381, Illumina NextSeq 550 System)
SCR_018169https://scicrunch.org/resolver/SCR_018169 SciCrunch identifier (RRID:SCR_018169, Leica SP8 LIGHTNING confocal microscope)
SCR_004726https://scicrunch.org/resolver/SCR_004726 SciCrunch identifier (RRID:SCR_004726, Pfam)
SCR_010246https://scicrunch.org/resolver/SCR_010246 SciCrunch identifier (RRID:SCR_010246, PSIPRED (Workbench))
SCR_001905https://scicrunch.org/resolver/SCR_001905 SciCrunch identifier (RRID:SCR_001905, R Project for Statistical Computing)
SCR_015899https://scicrunch.org/resolver/SCR_015899 SciCrunch identifier (RRID:SCR_015899, STAR)
SCR_002380https://scicrunch.org/resolver/SCR_002380 SciCrunch identifier (RRID:SCR_002380, UniProt)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41586-025-10058-2/MediaObjects/41586_2025_10058_MOESM1_ESM.pdf Supplemental material (figure)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41586-025-10058-2/MediaObjects/41586_2025_10058_MOESM2_ESM.pdf Supplemental material (reporting summary)
10.5281/zenodo.17886707https://doi.org/10.5281/zenodo.17886707 Zenodo identifier (10.5281/zenodo.17886707)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0219 |
 |
primary |
Sec61α |
|
Sec61α Antikörper (G-2) |
| secondary-0185 |
 |
secondary |
|
AB_621847 |
IRDye® 800CW Donkey anti-Mouse IgG Secondary Antibody |