| Property |
Value |
| Working Groups |
RG Urlaub |
| Subproject |
P04 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
40033019 |
| DOI |
10.1038/s44318-025-00400-9 |
| Publication Year |
2025 |
| Title |
PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division |
| Journal |
EMBO Journal |
| ISSN |
1460-2075 |
| eISSN |
0261-4189 |
| URL |
https://doi.org/10.1038/s44318-025-00400-9 |
| Journal Abbreviation |
EMBO J |
| Authors |
Gobran M, Politi AZ, Welp L, Jakobi J, Urlaub H, Lenart P |
| First Author |
Gobran M |
| Last Author |
Lenart P |
External Resources
embopres...d=truehttps://www.embopress.org/doi/pdf/10.1038/s44318-025-00400-9?download=true Article fulltext
10.17617/3.OYMBJ9https://doi.org/10.17617/3.OYMBJ9 DOI (10.17617/3.OYMBJ9, Edmond dataset)
S-SCDT-1...400-9)https://www.ebi.ac.uk/biostudies/studies/S-SCDT-10_1038-S44318-025-00400-9) EMBL-EBI biostudies identifier (S-SCDT-10_1038-S44318-025-00400-9)
gro-2/148466http://resolver.sub.uni-goettingen.de/purl?gro-2/148466 GRO.publications identifier
0009-0005-0487-878Xhttps://orcid.org/0009-0005-0487-878X ORCID identifier (Monica Gobran)
0000-0003-4788-0933https://orcid.org/0000-0003-4788-0933 ORCID identifier (Antonio Z. Politi)
0000-0003-0846-5200https://orcid.org/0000-0003-0846-5200 ORCID identifier (Luisa M. Welp)
0000-0003-1837-5233https://orcid.org/0000-0003-1837-5233 ORCID identifier (Henning Urlaub)
0000-0002-3927-248Xhttps://orcid.org/0000-0002-3927-248X ORCID identifier (Peter Lénárt)
PXD060406http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD060406 Pride proteome dataset (PXD060406)
4/23https://rdp.sfb1565.uni-goettingen.de/archive/4/23 Research Data Archive (supplemental material)
03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
CVCL_1922https://scicrunch.org/resolver/CVCL_1922 SciCrunch identifier (RRID:CVCL_1922, HeLa Kyoto)
CVCL_4388https://scicrunch.org/resolver/CVCL_4388 SciCrunch identifier (RRID:CVCL_4388, hTERT-RPE1)
CVCL_0042https://scicrunch.org/resolver/CVCL_0042 SciCrunch identifier (RRID:CVCL_0042, U2OS)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_006164https://scicrunch.org/resolver/SCR_006164 SciCrunch identifier (RRID:SCR_006164, Knime)
SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)
SCR_014485https://scicrunch.org/resolver/SCR_014485 SciCrunch identifier (RRID:SCR_014485, MaxQuant)
SCR_016137https://scicrunch.org/resolver/SCR_016137 SciCrunch identifier (RRID:SCR_016137, Microsoft Excel)
SCR_015753https://scicrunch.org/resolver/SCR_015753 SciCrunch identifier (RRID:SCR_015753, Perseus)
SCR_000432https://scicrunch.org/resolver/SCR_000432 SciCrunch identifier (RRID:SCR_000432, RStudio)
SCR_022546https://scicrunch.org/resolver/SCR_022546 SciCrunch identifier (RRID:SCR_022546, VisiView)
SCR_001996https://scicrunch.org/resolver/SCR_001996 SciCrunch identifier (RRID:SCR_001996, XPP-Aut: X-Windows Phase Plane plus Auto)
embopres...sm.pdfhttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm1_esm.pdf Supplemental material
embopres...m.docxhttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm2_esm.docx Supplemental material (table)
embopres...sm.txthttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm4_esm.txt Supplemental material
embopres...m.xlsxhttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm5_esm.xlsx Supplemental material (table)
embopres...m.xlsxhttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm6_esm.xlsx Supplemental material (table)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0017 |
|
primary |
H2AX |
AB_309864 |
Anti-phospho-Histone H2A.X (Ser139) Antibody |
| primary-0154 |
|
primary |
H31T |
AB_310177 |
Anti-Phospho-Histon H3 (Ser10)-Antikörper, Mitosemarker |
| primary-0155 |
|
primary |
|
AB_395288 |
Purified Mouse Anti-Cyclin B1 |
| primary-0159 |
|
primary |
MPIP3 |
AB_560956 |
cdc25C (5H9) Rabbit mAb |
| primary-0160 |
|
primary |
MPIP3 |
AB_331486 |
Phospho-cdc25C (Thr48) Antibody |
| primary-0161 |
|
primary |
CDK1 |
AB_331460 |
Phospho-cdc2 (Tyr15) Antibody |
| primary-0162 |
|
primary |
CDK1 |
AB_10979734 |
CDK1 Monoclonal Antibody (A17.1.1) |
| secondary-0156 |
|
secondary |
|
AB_2721875 |
Alexa Fluor® 594 AffiniPure™ Alpaca Anti-Rabbit IgG (H+L) |
| secondary-0157 |
|
secondary |
|
AB_2721890 |
Alexa Fluor® 594 AffiniPure™ Alpaca Anti-Mouse IgG (H+L) |
| secondary-0158 |
|
secondary |
|
AB_2721889 |
Alexa Fluor® 488 AffiniPure™ Alpaca Anti-Mouse IgG (H+L) |