| Property |
Value |
| Working Groups |
RG Papantonis |
| Subproject |
P03 |
| Open Access |
No |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
41444469 |
| DOI |
10.1038/s41556-025-01819-2 |
| Publication Year |
2025 |
| Title |
Two distinct chromatin modules regulate proinflammatory gene expression |
| Journal |
Nature Cell Biology |
| ISSN |
1465-7392 |
| eISSN |
1476-4679 |
| URL |
https://doi.org/10.1038/s41556-025-01819-2 |
| Pages |
182-196 |
| Issue |
1 |
| Volume |
28 |
| Journal Abbreviation |
Nat Cell Biol |
| Authors |
Seufert I, Gerosa I, Varamogianni-Mamatsi V, Vladimirova A, Sen E, Mantz S, Rademacher A, Schumacher S, Liakopoulos P, Kolovos P, Anders S, Mallm J, Papantonis A, Rippe K |
| First Author |
Seufert I |
| Last Author |
Rippe K |
External Resources
nature.c...-2.pdfhttps://www.nature.com/articles/s41556-025-01819-2.pdf Article fulltext
10.6019/S-BIAD1294https://doi.org/10.6019/S-BIAD1294 DOI (10.6019/S-BIAD1294, BioImage Archive)
gro-2/153518http://resolver.sub.uni-goettingen.de/purl?gro-2/153518 GRO.publications identifier
GSE273426https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE273426 NCBI GEO Dataset (GSE273426)
GSE273427https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE273427 NCBI GEO Dataset (GSE273427)
GSE273428https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE273428 NCBI GEO Dataset (GSE273428)
GSE273429https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE273429 NCBI GEO Dataset (GSE273429)
GSE274452https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE274452 NCBI GEO Dataset (GSE274452)
GSE63525https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63525 NCBI GEO Dataset (GSE63525, reused)
GSM7504073https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM7504073 NCBI GEO Dataset (GSM7504073, reused)
GSE160764https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE160764 NCBI GEO Dataset (GSE160764, reused)
GSE234226https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE234226 NCBI GEO Dataset (GSE234226, reused)
SRP066044https://www.ncbi.nlm.nih.gov/sra/SRP066044 NCBI SRA Dataset (SRP066044)
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
0000-0001-9811-3836https://orcid.org/0000-0001-9811-3836 ORCID identifier (Isabelle Seufert)
0009-0009-5468-7868https://orcid.org/0009-0009-5468-7868 ORCID identifier (Irene Gerosa)
0009-0006-7800-9920https://orcid.org/0009-0006-7800-9920 ORCID identifier (Vassiliki Varamogianni-Mamatsi)
0009-0009-5789-7051https://orcid.org/0009-0009-5789-7051 ORCID identifier (Anastasiya Vladimirova)
0009-0005-0816-2076https://orcid.org/0009-0005-0816-2076 ORCID identifier (Ezgi Sen)
0009-0001-7595-2693https://orcid.org/0009-0001-7595-2693 ORCID identifier (Stefanie Mantz)
0000-0003-3054-3121https://orcid.org/0000-0003-3054-3121 ORCID identifier (Anne Rademacher)
0000-0003-2292-9286https://orcid.org/0000-0003-2292-9286 ORCID identifier (Sabrina Schumacher)
0000-0002-0065-8764https://orcid.org/0000-0002-0065-8764 ORCID identifier (Panagiotis Liakopoulos)
0000-0002-0787-6158https://orcid.org/0000-0002-0787-6158 ORCID identifier (Petros Kolovos)
0000-0003-4868-1805https://orcid.org/0000-0003-4868-1805 ORCID identifier (Simon Anders)
0000-0002-7059-4030https://orcid.org/0000-0002-7059-4030 ORCID identifier (Jan-Philipp Mallm)
0000-0001-7551-1073https://orcid.org/0000-0001-7551-1073 ORCID identifier (Argyris Papantonis)
0000-0001-9951-9395https://orcid.org/0000-0001-9951-9395 ORCID identifier (Karsten Rippe)
54https://rdp.sfb1565.uni-goettingen.de/literature/publications/54 Published Data Registry entry (CRC 1565, preprint)
5/48https://rdp.sfb1565.uni-goettingen.de/archive/5/48 Research Data Archive (supplemental material)
03bfqnx40https://ror.org/03bfqnx40 ROR identifier (03bfqnx40, Democritus University of Thrace)
04cdgtt98https://ror.org/04cdgtt98 ROR identifier (04cdgtt98, German Cancer Research Center)
038t36y30https://ror.org/038t36y30 ROR identifier (038t36y30, Heidelberg University)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
SCR_020982https://scicrunch.org/resolver/SCR_020982 SciCrunch identifier (RRID:SCR_020982, ArchR)
SCR_016368https://scicrunch.org/resolver/SCR_016368 SciCrunch identifier (RRID:SCR_016368, Bowtie 2)
SCR_017344https://scicrunch.org/resolver/SCR_017344 SciCrunch identifier (RRID:SCR_017344, Cell Ranger)
SCR_021716https://scicrunch.org/resolver/SCR_021716 SciCrunch identifier (RRID:SCR_021716, Cellpose)
SCR_026570https://scicrunch.org/resolver/SCR_026570 SciCrunch identifier (RRID:SCR_026570, chromvar)
SCR_002344https://scicrunch.org/resolver/SCR_002344 SciCrunch identifier (RRID:SCR_002344, Ensembl)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_000025https://scicrunch.org/resolver/SCR_000025 SciCrunch identifier (RRID:SCR_000025, GenomicRanges)
SCR_002630https://scicrunch.org/resolver/SCR_002630 SciCrunch identifier (RRID:SCR_002630, GitHub)
SCR_016381https://scicrunch.org/resolver/SCR_016381 SciCrunch identifier (RRID:SCR_016381, Illumina NextSeq 550 System)
SCR_016387https://scicrunch.org/resolver/SCR_016387 SciCrunch identifier (RRID:SCR_016387, Illumina NovaSeq 6000 Sequencing System)
SCR_013291https://scicrunch.org/resolver/SCR_013291 SciCrunch identifier (RRID:SCR_013291, MACS)
SCR_024135https://scicrunch.org/resolver/SCR_024135 SciCrunch identifier (RRID:SCR_024135, Nextflow)
SCR_001905https://scicrunch.org/resolver/SCR_001905 SciCrunch identifier (RRID:SCR_001905, R Project for Statistical Computing)
SCR_008058https://scicrunch.org/resolver/SCR_008058 SciCrunch identifier (RRID:SCR_008058, SciPy)
SCR_007322https://scicrunch.org/resolver/SCR_007322 SciCrunch identifier (RRID:SCR_007322, Seurat)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41556-025-01819-2/MediaObjects/41556_2025_1819_MOESM1_ESM.pdf Supplemental material
github.com/RippeLab/RWireXhttps://github.com/RippeLab/RWireX Supplemental material (code)
github.c...oscopyhttps://github.com/RippeLab/ACDC-microscopy Supplemental material (code)
goeseek.gwdguser.de/studies/278https://goeseek.gwdguser.de/studies/278 Supplemental material (goeseek study)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41556-025-01819-2/MediaObjects/41556_2025_1819_MOESM3_ESM.pdf Supplemental material (peer review)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41556-025-01819-2/MediaObjects/41556_2025_1819_MOESM2_ESM.pdf Supplemental material (reporting summary)
static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41556-025-01819-2/MediaObjects/41556_2025_1819_MOESM6_ESM.xlsx Supplemental material (source data)
static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41556-025-01819-2/MediaObjects/41556_2025_1819_MOESM4_ESM.xlsx Supplemental material (table)
static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41556-025-01819-2/MediaObjects/41556_2025_1819_MOESM5_ESM.xlsx Supplemental material (table)
10.5281/zenodo.13142236https://doi.org/10.5281/zenodo.13142236 Zenodo identifier (10.5281/zenodo.13142236)
10.5281/zenodo.13221210https://doi.org/10.5281/zenodo.13221210 Zenodo identifier (10.5281/zenodo.13221210)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0240 |
|
primary |
RELA |
|
primary antibody (NF-κB p65 (D14E12) XP Rabbit mAb |
| primary-0246 |
|
primary |
|
AB_2904604 |
H3K27ac antibody |
| primary-0247 |
|
primary |
|
AB_2118291 |
H3K27ac antibody |
| secondary-0248 |
|
secondary |
|
AB_2535812 |
secondary antibody (goat anti-Rabbit IgG (H+L) labelled with Alexa Fluor 647 |