| Property |
Value |
| Working Groups |
RG Oudelaar, 
RG Papantonis |
| Subproject |
P02, P03 |
| Open Access |
Yes |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.1101/2024.07.16.603680 |
| Publication Year |
2024 |
| Title |
Senescent cells cluster CTCF on nuclear speckles to sustain their splicing program |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
https://doi.org/10.1101/2024.07.16.603680 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Final article published in Nature Aging here: doi:DOI not yet available, in press |
| Authors |
Palikyras S, Varamogiani-Mamatsi V, Zhu Y, Ramasamy S, Mizi A, Liebermann I, Stavropoulou A, Papadionysiou I, Bartsch D, Kargapolova Y, Sofiadis K, Nikolaou C, Kurian L, Oudelaar AM, Barbieri M, Papantonis A |
| First Author |
Palikyras S |
| Last Author |
Papantonis A |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2024.07.16.603680v1.full.pdf Article fulltext
2/153270https://publications.goettingen-research-online.de/handle/2/153270 GRO.publications identifier
GSE269856https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE269856 NCBI GEO Dataset (GSE269856)
GSE269857https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE269857 NCBI GEO Dataset (GSE269857)
GSE269858https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE269858 NCBI GEO Dataset (GSE269858)
GSE171782https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE171782 NCBI GEO Dataset (GSE171782, reused)
GSE238256https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE238256 NCBI GEO Dataset (GSE238256, reused)
0000-0002-4470-8284https://orcid.org/0000-0002-4470-8284 ORCID identifier (Spyridon Palikyras)
0009-0006-7800-9920https://orcid.org/0009-0006-7800-9920 ORCID identifier (Vassiliki Varamogianni-Mamatsi)
0000-0003-0617-694Xhttps://orcid.org/0000-0003-0617-694X ORCID identifier (Shyam Ramasamy)
0000-0002-4313-491Xhttps://orcid.org/0000-0002-4313-491X ORCID identifier (Athanasia Mizi)
0009-0002-3263-0990https://orcid.org/0009-0002-3263-0990 ORCID identifier (Athanasia Stavropoulou)
0000-0003-3299-8330https://orcid.org/0000-0003-3299-8330 ORCID identifier (Deniz Bartsch)
0000-0001-7541-5778https://orcid.org/0000-0001-7541-5778 ORCID identifier (Yulia Kargapolova)
0009-0000-0167-8372https://orcid.org/0009-0000-0167-8372 ORCID identifier (Konstantinos Sofiadis)
0000-0003-3001-6786https://orcid.org/0000-0003-3001-6786 ORCID identifier (Christoforos Nikolaou)
0000-0001-7466-5169https://orcid.org/0000-0001-7466-5169 ORCID identifier (Leo Kurian)
0000-0002-3425-0476https://orcid.org/0000-0002-3425-0476 ORCID identifier (A. Marieke Oudelaar)
0000-0002-9080-631Xhttps://orcid.org/0000-0002-9080-631X ORCID identifier (Mariano Barbieri)
0000-0001-7551-1073https://orcid.org/0000-0001-7551-1073 ORCID identifier (Argyris Papantonis)
134https://rdp.sfb1565.uni-goettingen.de/literature/publications/134 Published Data Registry entry (CRC 1565, final article)
5/42https://rdp.sfb1565.uni-goettingen.de/archive/5/42 Research Data Archive (supplemental material)
013x0ky90https://ror.org/013x0ky90 ROR identifier (013x0ky90, Alexander Fleming Biomedical Sciences Research Center)
04cvxnb49https://ror.org/04cvxnb49 ROR identifier (04cvxnb49, Goethe University Frankfurt)
03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
00rcxh774https://ror.org/00rcxh774 ROR identifier (00rcxh774, University of Cologne)
SCR_006646https://scicrunch.org/resolver/SCR_006646 SciCrunch identifier (RRID:SCR_006646, BEDTools)
SCR_016366https://scicrunch.org/resolver/SCR_016366 SciCrunch identifier (RRID:SCR_016366, Deeptools)
SCR_015687https://scicrunch.org/resolver/SCR_015687 SciCrunch identifier (RRID:SCR_015687, DESeq2)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_005514https://scicrunch.org/resolver/SCR_005514 SciCrunch identifier (RRID:SCR_005514, HTSeq)
SCR_016387https://scicrunch.org/resolver/SCR_016387 SciCrunch identifier (RRID:SCR_016387, Illumina: NovaSeq 6000 Sequencing System)
SCR_016386https://scicrunch.org/resolver/SCR_016386 SciCrunch identifier (RRID:SCR_016386, Illumina HiSeq 3000/HiSeq 4000 Sequencing System)
SCR_027320https://scicrunch.org/resolver/SCR_027320 SciCrunch identifier (RRID:SCR_027320, IsoformSwitchAnalyzeR)
SCR_026672https://scicrunch.org/resolver/SCR_026672 SciCrunch identifier (RRID:SCR_026672, Leica: DMi8 Inverted Microscope)
SCR_016620https://scicrunch.org/resolver/SCR_016620 SciCrunch identifier (RRID:SCR_016620, Metascape)
SCR_006525https://scicrunch.org/resolver/SCR_006525 SciCrunch identifier (RRID:SCR_006525, Picard)
SCR_006263https://scicrunch.org/resolver/SCR_006263 SciCrunch identifier (RRID:SCR_006263, RUVSeq)
SCR_017036https://scicrunch.org/resolver/SCR_017036 SciCrunch identifier (RRID:SCR_017036, salmon)
SCR_004463https://scicrunch.org/resolver/SCR_004463 SciCrunch identifier (RRID:SCR_004463, STAR)
SCR_015872https://scicrunch.org/resolver/SCR_015872 SciCrunch identifier (RRID:SCR_015872, UCSF ChimeraX)
SCR_018349https://scicrunch.org/resolver/SCR_018349 SciCrunch identifier (RRID:SCR_018349, Whippet)
github.com/varamojo/SimChromhttps://github.com/varamojo/SimChrom Supplemental material (code, reused)
goeseek.gwdguser.de/studies/274https://goeseek.gwdguser.de/studies/274 Supplemental material (goeseek study)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2024/07/16/2024.07.16.603680/DC1/embed/media-1.xlsx?download=true Supplemental material (table)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2024/07/16/2024.07.16.603680/DC2/embed/media-2.xlsx?download=true Supplemental material (table)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2024/07/16/2024.07.16.603680/DC3/embed/media-3.xlsx?download=true Supplemental material (table)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2024/07/16/2024.07.16.603680/DC4/embed/media-4.xlsx?download=true Supplemental material (table)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2024/07/16/2024.07.16.603680/DC5/embed/media-5.xlsx?download=true Supplemental material (table)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0003 |
|
primary |
HMGB1 |
|
Anti-HMGB1 antibody [1F3] |
| primary-0005 |
|
primary |
CTCF |
AB_2614975 |
CTCF antibody (pAb) |
| primary-0394 |
|
primary |
SRRM2 |
AB_2647934 |
SRRM2 Polyclonal Antibody |
| primary-0395 |
|
primary |
SRSF2 |
AB_526734 |
SC35 Antibody (SC-35) |
| secondary-0008 |
|
secondary |
|
AB_2630356 |
Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) |
| secondary-0009 |
|
secondary |
|
AB_10680176 |
Goat Anti-Mouse IgG H&L (Cy3 ®) preadsorbed |