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Publication

Property	Value
Working Groups	RG Lorenz, RG Urlaub
Subproject	None
Open Access	Yes
Publication Type	Journal Article
Peer Reviewed	Yes
PMID	38316879
DOI	10.1038/s41594-023-01207-0
Publication Year	2024
Title	Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair
Journal	Nature Structural & Molecular Biology
ISSN	1545-9993
eISSN	1545-9985
URL	http://dx.doi.org/10.1038/s41594-023-01207-0
Journal Abbreviation	Nat Struct Mol Biol
Authors	Kokic G, Yakoub G, van den Heuvel D, Wondergem AP, van der Meer PJ, van der Weegen Y, Chernev A, Fianu I, Fokkens TJ, Lorenz S, Urlaub H, Cramer P, Luijsterburg MS
First Author	Kokic G
Last Author	Luijsterburg MS

External Resources

nature.c...-0.pdfhttps://www.nature.com/articles/s41594-023-01207-0.pdf Article fulltext

EMD-15825https://www.ebi.ac.uk/pdbe/emdb/EMD-15825 EMBL-EBI EMDB identifier (EMD-15825)

EMD-15827https://www.ebi.ac.uk/pdbe/emdb/EMD-15827 EMBL-EBI EMDB identifier (EMD-15827)

EMD-15829https://www.ebi.ac.uk/pdbe/emdb/EMD-15829 EMBL-EBI EMDB identifier (EMD-15829)

7108https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=7108 NCBI taxonomy (fall armyworm, Spodoptera frugiperda)

9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)

0000-0001-8912-7099https://orcid.org/0000-0001-8912-7099 ORCID identifier (Goran Kokic)

0000-0003-2727-7651https://orcid.org/0000-0003-2727-7651 ORCID identifier (George Yakoub)

0000-0001-7616-6689https://orcid.org/0000-0001-7616-6689 ORCID identifier (Paula Johanna van der Meer)

0000-0002-8508-114Xhttps://orcid.org/0000-0002-8508-114X ORCID identifier (Isaac Fianu)

0000-0002-9639-2381https://orcid.org/0000-0002-9639-2381 ORCID identifier (Sonja Gisela Lorenz)

0000-0003-1837-5233https://orcid.org/0000-0003-1837-5233 ORCID identifier (Henning Urlaub)

0000-0001-5454-7755https://orcid.org/0000-0001-5454-7755 ORCID identifier (Patrick Cramer)

0000-0001-5796-6541https://orcid.org/0000-0001-5796-6541 ORCID identifier (Martijn S. Luijsterburg)

PXD042388http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD042388 Pride proteome dataset (PXD042388)

8B3Dhttps://www.rcsb.org/structure/8B3D RCSB PDB Identifier (DOI:10.2210/pdb 8B3D/pdb)

8B3Ghttps://www.rcsb.org/structure/8B3G RCSB PDB Identifier (DOI:10.2210/pdb8B3G/pdb)

8B3Ihttps://www.rcsb.org/structure/8B3I RCSB PDB Identifier (DOI:10.2210/pdb8B3I/pdb)

1PQVhttps://www.rcsb.org/structure/1PQV RCSB PDB Identifier (DOI:10.2210/pdb1PQV/pdb, reused)

6TTUhttps://www.rcsb.org/structure/6TTU RCSB PDB Identifier (DOI:10.2210/pdb6TTU/pdb, reused)

7OO3https://www.rcsb.org/structure/7OO3 RCSB PDB Identifier (DOI:10.2210/pdb7OO3/pdb, reused)

4/12https://rdp.sfb1565.uni-goettingen.de/archive/4/12 Research Data Archive (supplemental material)

027bh9e22https://ror.org/027bh9e22 ROR identifier (027bh9e22, Leiden University)

03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)

021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)

CVCL_0063https://scicrunch.org/resolver/CVCL_0063 SciCrunch identifier (RRID:CVCL_0063, HEK293T)

CVCL_0518https://scicrunch.org/resolver/CVCL_0518 SciCrunch identifier (RRID:CVCL_0518, Sf21)

CVCL_0549https://scicrunch.org/resolver/CVCL_0549 SciCrunch identifier (RRID:CVCL_0549, Sf9)

CVCL_0042https://scicrunch.org/resolver/CVCL_0042 SciCrunch identifier (RRID:CVCL_0042, U2OS)

SCR_010279https://scicrunch.org/resolver/SCR_010279 SciCrunch identifier (RRID:SCR_010279, Adobe Illustrator)

SCR_014222https://scicrunch.org/resolver/SCR_014222 SciCrunch identifier (RRID:SCR_014222, Coot)

SCR_016501https://scicrunch.org/resolver/SCR_016501 SciCrunch identifier (RRID:SCR_016501, cryoSPARC)

SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)

SCR_013715https://scicrunch.org/resolver/SCR_013715 SciCrunch identifier (RRID:SCR_013715, Image Studio Lite)

SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)

SCR_016137https://scicrunch.org/resolver/SCR_016137 SciCrunch identifier (RRID:SCR_016137, Microsoft Excel)

SCR_014226https://scicrunch.org/resolver/SCR_014226 SciCrunch identifier (RRID:SCR_014226, MolProbity)

SCR_014224https://scicrunch.org/resolver/SCR_014224 SciCrunch identifier (RRID:SCR_014224, Phenix)

SCR_000084https://scicrunch.org/resolver/SCR_000084 SciCrunch identifier (RRID:SCR_000084, pLink)

SCR_018333https://scicrunch.org/resolver/SCR_018333 SciCrunch identifier (RRID:SCR_018333, PlotsOfData)

SCR_016274https://scicrunch.org/resolver/SCR_016274 SciCrunch identifier (RRID:SCR_016274, RELION)

SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)

SCR_004097https://scicrunch.org/resolver/SCR_004097 SciCrunch identifier (RRID:SCR_004097, UCSF Chimera)

SCR_018071https://scicrunch.org/resolver/SCR_018071 SciCrunch identifier (RRID:SCR_018071, Warp)

SCR_013672https://scicrunch.org/resolver/SCR_013672 SciCrunch identifier (RRID:SCR_013672, ZEN Digital Imaging for Light Microscopy)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM1_ESM.pdf Supplemental material

goeseek.gwdguser.de/studies/146https://goeseek.gwdguser.de/studies/146 Supplemental material (goeseek study)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM2_ESM.pdf Supplemental material (reporting summary)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM3_ESM.pdf Supplemental material (peer review)

static-c...SM.mp4https://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM4_ESM.mp4 Supplemental material (video)

static-c...SM.mp4https://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM5_ESM.mp4 Supplemental material (video)

static-c...SM.mp4https://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM6_ESM.mp4 Supplemental material (video)

static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM7_ESM.xlsx Supplemental material (source data)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM8_ESM.pdf Supplemental material (source data)

static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM9_ESM.xlsx Supplemental material (source data)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM10_ESM.pdf Supplemental material (source data)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM11_ESM.pdf Supplemental material (source data)

static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM12_ESM.xlsx Supplemental material (source data)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM13_ESM.pdf Supplemental material (source data)

static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM14_ESM.xlsx Supplemental material (source data)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM15_ESM.pdf Supplemental material (source data)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM16_ESM.pdf Supplemental material (source data)

static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM17_ESM.xlsx Supplemental material (source data)

static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM18_ESM.xlsx Supplemental material (source data)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM19_ESM.pdf Supplemental material (source data)

static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41594-023-01207-0/MediaObjects/41594_2023_1207_MOESM20_ESM.pdf Supplemental material (source data)

Linked Antibodies

PID	Type	Antigen symbol	Antibody Registry ID	Name
primary-0014	primary	GFP	AB_390913	Anti-GFP antibody
primary-0015	primary	GFP	AB_303395	Anti-GFP antibody
primary-0017	primary	H2AX	AB_309864	Anti-phospho-Histone H2A.X (Ser139) Antibody
primary-0018	primary	TUBA4A	AB_477583	Anti-α-Tubulin antibody
primary-0019	primary			CSA Antikörper (D-2)
primary-0020	primary	ERCC8	AB_2783825	Anti-ERCC8 antibody [EPR9237]
primary-0021	primary		AB_668958	CSB Antikörper (H-300)
primary-0022	primary	ERCC6	Bethyl A301-345A	CSB/ERCC6 Polyclonal Antibody
primary-0025	primary		AB_2247962	TFIIH p62 Antikörper (G-10)
primary-0026	primary	XPB		Anti-XPB Antibody, clone 15TF2-1B3
primary-0027	primary	RPO21	AB_304749	Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S2) antibody
primary-0030	primary	RPB1		RPB1
primary-0031	primary		AB_2051891	Mono- and polyubiquitinylated conjugates monoclonal antibody (FK2)
primary-0032	primary	RL40	AB_331292	Ubiquitin (P4D1) Mouse mAb
secondary-0002	secondary		AB_10719218	Goat-anti-rabbit IgG (H+L), HRP conjugate antibody
secondary-0016	secondary		AB_141780	Goat anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 555
secondary-0023	secondary			Goat anti-Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 647
secondary-0024	secondary		AB_10559194	Goat Anti-Mouse IgG (H+L), Highly Cross-Adsorbed
secondary-0028	secondary		AB_10582887	Goat Anti-Rabbit IgG (H+L), Highly Cross-Adsorbed

Department of Medical Informatics
University Medical Center Göttingen
Imprint

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External Resources

Linked Antibodies

Technical support

Links

Speaker

Prof. Dr. Markus T. Bohnsack

Speaker of SFB1565