Property | Value |
Working Groups | RG Urlaub |
Subproject | P04 |
Open Access | Yes |
Publication Type | Journal Article |
Peer Reviewed | Yes |
PMID | 40033019 |
DOI | 10.1038/s44318-025-00400-9 |
Publication Year | 2025 |
Title | PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division |
Journal | EMBO Journal |
ISSN | 1460-2075 |
eISSN | 0261-4189 |
URL | https://doi.org/10.1038/s44318-025-00400-9 |
Journal Abbreviation | EMBO J |
Authors | Gobran M, Politi AZ, Welp L, Jakobi J, Urlaub H, Lenart P |
First Author | Gobran M |
Last Author | Lenart P |
External Resources
embopres...d=truehttps://www.embopress.org/doi/pdf/10.1038/s44318-025-00400-9?download=true
Article fulltext
0009-0005-0487-878Xhttps://orcid.org/0009-0005-0487-878X
ORCID identifier (Monica Gobran)
0000-0003-4788-0933https://orcid.org/0000-0003-4788-0933
ORCID identifier (Antonio Z. Politi)
0000-0003-0846-5200https://orcid.org/0000-0003-0846-5200
ORCID identifier (Luisa M. Welp)
0000-0003-1837-5233https://orcid.org/0000-0003-1837-5233
ORCID identifier (Henning Urlaub)
0000-0002-3927-248Xhttps://orcid.org/0000-0002-3927-248X
ORCID identifier (Peter Lénárt)
4/23https://rdp.sfb1565.uni-goettingen.de/archive/4/23
Research Data Archive (supplemental material)
03av75f26https://ror.org/03av75f26
ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
021ft0n22https://ror.org/021ft0n22
ROR identifier (021ft0n22, University Medical Center Göttingen)
CVCL_1922https://scicrunch.org/resolver/CVCL_1922
SciCrunch identifier (RRID:CVCL_1922, HeLa Kyoto)
CVCL_4388https://scicrunch.org/resolver/CVCL_4388
SciCrunch identifier (RRID:CVCL_4388, hTERT-RPE1)
CVCL_0042https://scicrunch.org/resolver/CVCL_0042
SciCrunch identifier (RRID:CVCL_0042, U2OS)
SCR_002285https://scicrunch.org/resolver/SCR_002285
SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_006164https://scicrunch.org/resolver/SCR_006164
SciCrunch identifier (RRID:SCR_006164, Knime)
SCR_001622https://scicrunch.org/resolver/SCR_001622
SciCrunch identifier (RRID:SCR_001622, MATLAB)
SCR_014485https://scicrunch.org/resolver/SCR_014485
SciCrunch identifier (RRID:SCR_014485, MaxQuant)
SCR_016137https://scicrunch.org/resolver/SCR_016137
SciCrunch identifier (RRID:SCR_016137, Microsoft Excel)
SCR_015753https://scicrunch.org/resolver/SCR_015753
SciCrunch identifier (RRID:SCR_015753, Perseus)
SCR_000432https://scicrunch.org/resolver/SCR_000432
SciCrunch identifier (RRID:SCR_000432, RStudio)
SCR_022546https://scicrunch.org/resolver/SCR_022546
SciCrunch identifier (RRID:SCR_022546, VisiView)
SCR_001996https://scicrunch.org/resolver/SCR_001996
SciCrunch identifier (RRID:SCR_001996, XPP-Aut: X-Windows Phase Plane plus Auto)
embopres...sm.pdfhttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm1_esm.pdf
Supplemental material
embopres...m.docxhttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm2_esm.docx
Supplemental material (table)
embopres...sm.txthttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm4_esm.txt
Supplemental material
embopres...m.xlsxhttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm5_esm.xlsx
Supplemental material (table)
embopres...m.xlsxhttps://www.embopress.org/doi/suppl/10.1038/s44318-025-00400-9/suppl_file/44318_2025_400_moesm6_esm.xlsx
Supplemental material (table)
Linked Antibodies
PID | AG | Type | Antigen symbol | Antibody Registry ID | Name |
primary-0017 |  | primary | H2AX | AB_309864 | Anti-phospho-Histone H2A.X (Ser139) Antibody |
primary-0154 |  | primary | H31T | AB_310177 | Anti-Phospho-Histon H3 (Ser10)-Antikörper, Mitosemarker |
primary-0155 |  | primary | | AB_395288 | Purified Mouse Anti-Cyclin B1 |
primary-0159 |  | primary | MPIP3 | AB_560956 | cdc25C (5H9) Rabbit mAb |
primary-0160 |  | primary | MPIP3 | AB_331486 | Phospho-cdc25C (Thr48) Antibody |
primary-0161 |  | primary | CDK1 | AB_331460 | Phospho-cdc2 (Tyr15) Antibody |
primary-0162 |  | primary | CDK1 | AB_10979734 | CDK1 Monoclonal Antibody (A17.1.1) |
secondary-0156 |  | secondary | | AB_2721875 | Alexa Fluor® 594 AffiniPure™ Alpaca Anti-Rabbit IgG (H+L) |
secondary-0157 |  | secondary | | AB_2721890 | Alexa Fluor® 594 AffiniPure™ Alpaca Anti-Mouse IgG (H+L) |
secondary-0158 |  | secondary | | AB_2721889 | Alexa Fluor® 488 AffiniPure™ Alpaca Anti-Mouse IgG (H+L) |